PubMed record for E GluenzRecent Publications
2025
Andreia Albuquerque-Wendt, Ciaran McCoy, Rachel Neish, Ulrich Dobramysl, Çağla Alagöz, Tom Beneke, Sally A. Cowley, Kathryn Crouch, Richard J. Wheeler, Jeremy C. Mottram, Eva Gluenz. TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen. Nat Commun 16, 299 (2025).
2024
PREPRINT: Tom Beneke, Rachel Neish, Carolina M. C. Catta-Preta, James Smith, Jessica Valli, Ciaran J. McCoy, Andreia Albuquerque-Wendt, Jeremy C. Mottram, Eva Gluenz. IFT and BBSome proteins are required for Leishmania mexicana pathogenicity, but flagellar motility is dispensable. bioRxiv 2024.09.13.612850; doi: https://doi.org/10.1101/2024.09.13.612850
The LeishGEM Team. LeishGEM: genome-wide deletion mutant fitness and protein localisations in Leishmania. Trends Parasitol. 2024 Jul 18:S1471-4922(24)00143-0. doi: 10.1016/j.pt.2024.06.003.
PREPRINT: Andreia Albuquerque-Wendt, Ciaran McCoy, Rachel Neish, Ulrich Dobramysl, Tom Beneke, Sally A. Cowley, Kathryn Crouch, Richard J. Wheeler, Jeremy C. Mottram, Eva Gluenz. TransLeish: Identification of membrane transporters essential for survival of intracellular Leishmania parasites in a systematic gene deletion screen. bioRxiv 2024.06.21.600025; doi: https://doi.org/10.1101/2024.06.21.600025
2023
PREPRINT: Fochler S, Walker BJ, Wheeler RJ, Gluenz E. Divergent Protein Kinase A contributes to the regulation of flagellar waveform of the motile flagellum of Leishmania mexicana. bioRxiv 2023.11.08.566240; doi: https://doi.org/10.1101/2023.11.08.566240
McCoy CJ, Paupelin-Vaucelle H, Gorilak P, Beneke T, Varga V, Gluenz E. ULK4 and Fused/STK36 interact to mediate assembly of a motile flagellum. Mol Biol Cell. 2023 Jun 1;34(7):ar66. doi: 10.1091/mbc.E22-06-0222.
2022
Beneke T, Dobramysl U, Catta-Preta CMC et al. Genome sequence of Leishmania mexicana MNYC/BZ/62/M379 expressing Cas9 and T7 RNA polymerase. Wellcome Open Res 2022, 7:294 (https://doi.org/10.12688/wellcomeopenres.18575.1)
2021
Espada CR, Quilles JC Jr, Albuquerque-Wendt A, Cruz MC, Beneke T, Lorenzon LB, Gluenz E, Cruz AK, Uliana SRB (2021). Effective Genome Editing in Leishmania (Viannia) braziliensis Stably Expressing Cas9 and T7 RNA Polymerase. Front Cell Infect Microbiol. 11:772311. doi: 10.3389/fcimb.2021.772311.
Espada CR, Albuquerque-Wendt A, Hornillos V, Gluenz E, Coelho AC, Uliana SRB. (2021). Ros3 (Lem3p/CDC50) Gene Dosage Is Implicated in Miltefosine Susceptibility in Leishmania (Viannia) braziliensis Clinical Isolates and in Leishmania (Leishmania) major. ACS Infect. Dis. https://doi.org/10.1021/acsinfecdis.0c00857
2020
Beneke T, Gluenz E (2020) Bar-seq strategies for the LeishGEdit toolbox. Mol Miochem Parasitol 239:111295.
Wang Z, Beneke T, Gluenz E, Wheeler R (2020) The single flagellum of Leishmania has a fixed polarisation of its asymmetric beat. J Cell Sci. 22;133(20):jcs246637.
Beneke T, Demay F, Wheeler RJ and Gluenz E (2020) Isolation of Leishmania Promastigote Flagella. In: Michels P, Ginger M, Zilberstein D (eds) Trypanosomatids. Methods Mol Biol. 2116:485-95.
Beneke T, Banecki K, Fochler S and Gluenz E (2020) LAX28 is required for the stable assembly of the inner dynein arm f complex and the tether and tether head complex in Leishmania flagella. J Cell Sci 133: jcs239855
2019
Beneke T, Demay F, Hookway E, Ashman N, Jeffery H, Smith J, Valli J, Becvar T, Myskova J, Lestinova T, Sadlova J, Volf P, Wheeler RJ and Gluenz E (2019) Genetic dissection of the Leishmania flagellar proteome demonstrates requirement for directional motility in sand fly infections. PLoS Pathogens 15:e1007828.
Beneke T and Gluenz E (2019) LeishGEdit: a method for rapid gene knockout and tagging using CRISPR-Cas9. Methods Mol Biol. 1971:189-210.
Schädeli D, Serricchio M, Ben Hamidane H, Loffreda A, Hemphill A, Beneke T, Gluenz E, Graumann J, Bütikofer P (2019) Cardiolipin depletion-induced changes in the Trypanosoma brucei proteome. FASEB J. 19:fj201901184RR.
2018
Costa FC, Francisco AF, Jayawardhana S, Calderano SG, Lewis MD, Olmo F, Beneke T, Gluenz E, Sunter J, Dean S, Kelly JM and Taylor MC. (2018) Expanding the toolbox for Trypanosoma cruzi: A parasite line incorporating a bioluminescence-fluorescence dual reporter and streamlined CRISPR/Cas9 functionality for rapid in vivo localisation and phenotyping. PLoS NTD 12:e0006388.
Ooi C-P, Smith TK, Gluenz E, Wand NV, Vaughan S, Rudenko G. (2018) Blocking variant surface glycoprotein synthesis alters endoplasmic reticulum exit sites/Golgi homeostasis in Trypanosoma brucei. Traffic 1-15.
2017
Martel D, Beneke T, Gluenz E, Späth GF, Rachidi N. (2017) Characterisation of Casein kinase 1.1 in Leishmania donovani using the CRISPR Cas9 toolkit. BioMed Res. Int Article ID 4635605. doi:10.1155/2017/4635605.
Beneke T, Madden R, Makin L, Valli J, Sunter J, Gluenz E. (2017) A CRISPR Cas9 high-throughput genome editing toolkit for kinetoplastids. R Soc Open Sci. 4(5):170095.
2016
Sanchez MA, Tran KD, Valli J, Hobbs S, Johnson E, Gluenz E, Landfear SM. (2016) KHARON is an essential cytoskeletal protein involved in the trafficking of flagellar membrane proteins and cell division in African trypanosomes. J Biol Chem 291(38):19760-73.
2015
Wheeler RJ, Gluenz E, Gull K. (2015) Routes to a 9+0 flagellum: Basal body multipotency and axonemal plasticity. Nat Commun 6:8964.
Fiebig M. Kelly S, Gluenz E. (2015) Comparative life cycle transcriptomics revises Leishmania mexicana genome annotation and links a chromosome duplication with parasitism of vertebrates. PLoS Pathogens 11(10):e1005186.
Dean S, Sunter J, Wheeler R, Hodkinson I, Gluenz E, Gull K (2015) A toolkit enabling efficient, scalable and reproducible gene tagging in trypanosomatids. Open Biology 5(1):140197.
Tran KD, Vieira DP, Sanchez MA, Valli J, Gluenz E, Landfear SM. (2015) Kharon1 null mutants of Leishmania mexicana are avirulent in mice and exhibit a cytokinesis defect within macrophages. PLoS One 10:e0134432.
Gluenz E, Wheeler R J, Hughes L, Vaughan S. (2015) Scanning and three-dimensional electron microscopy methods for the study of Trypanosoma brucei and Leishmania mexicana flagella. Methods Cell Biol. 127:509-42.
Makin L, Gluenz E. (2015) cAMP signalling in trypanosomatids: role in pathogenesis and as a drug target. Trends Parasitol. 31:373-9.